Knoevenagel condensation of aldehydes with ethyl cyanoacetate in water catalyzed by P4VP/Al2O3-SiO2

Abstract

This paper reports the preparation and characterization of poly(4-vinylpyridine) (P4VP) supported on Al2O3-SiO 2 and its application for Knoevenagel condensation reaction of various aldehydes with ethyl cyanoacetate in water as a green solvent. The results illustrate that the sample containing 0.6 molar ratio of Al to Si exhibits the highest yield (98%) in the reaction of benzaldehyde with ethyl cyanoacetate with 100% selectivity to the arylidene derivative. © 2012 Majid Kolahdoozan et al.