Human skin is a niche for various fungal species which either colonize the surface of this tissue as commensals or, primarily under conditions of immunosuppression, invade the skin and cause infection. Here we present a method for generation of a human in vitro skin model supplemented with immune cells of choice. This model represents a complex yet amenable tool to study molecular mechanisms of host–fungi interactions at human skin.
CITATION STYLE
Kühbacher, A., Sohn, K., Burger-Kentischer, A., & Rupp, S. (2017). Immune cell-supplemented human skin model for studying fungal infections. In Methods in Molecular Biology (Vol. 1508, pp. 439–449). Humana Press Inc. https://doi.org/10.1007/978-1-4939-6515-1_25
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