Abstract
Several biocompatible carrier agents, in which xenon is highly soluble and has a long T1, were tested, and injected in living rats. These included saline, Intralipid suspension, perfluorocarbon emulsion and 129Xe gas- filled liposomes. The T1 of 129Xe in these compounds ranged from 47 to 116 s. Vascular injection of these carrier agents was tolerated well, encouraging their use for further experiments in live animals. In vivo spectra, obtained from gas-filled liposomes and perfluorocarbon solutions, suggest that these carrier agents have potential for use in angiography and perfusion imaging. Copyright (C) 2000 John Wiley and Sons, Ltd.
Author supplied keywords
Cite
CITATION STYLE
Venkatesh, A. K., Zhao, L., Balamore, D., Jolesz, F. A., & Albert, M. S. (2000). Evaluation of career agents for hyperpolarized xenon MRI. NMR in Biomedicine, 13(4), 245–252. https://doi.org/10.1002/1099-1492(200006)13:4<245::AID-NBM635>3.0.CO;2-7
Register to see more suggestions
Mendeley helps you to discover research relevant for your work.
