We describe a 23-year-old woman with previous right temporal lobe surgeries for underlying cortical dysplasia, presenting with drug-resistant right hemispheric seizures and epilepsia partialis continua (EPC). After anti-seizure medication adjustments, she developed focal status epilepticus with progressive EEG and neuroimaging changes. Cerebrospinal fluid and serum autoimmune panels were negative except for an elevated serum acetylcholine-receptor antibody titer, but she underwent immunosuppressive therapy. Stereotactic-EEG evaluation demonstrated multifocal independent ictal patterns in the right hemisphere. Rasmussen's Syndrome was confirmed by brain biopsy, and a hemispherectomy was performed. This patient demonstrates the rare association of adult-onset EPC with cortical dysplasia, precipitously evolving into Rasmussen's Syndrome.
CITATION STYLE
Szabó, C. Á., Garvin, R., Hafeez, S., Seifi, A., Leary, L., Bhavaraju-Sanka, R., … Papanastassiou, A. M. (2019). Adult-onset Rasmussen’s Syndrome with associated cortical dysplasia. Epilepsy and Behavior Case Reports, 11, 54–57. https://doi.org/10.1016/j.ebcr.2018.11.004
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