Automated peptide mapping and protein-topographical annotation of proteomics data

0Citations
Citations of this article
22Readers
Mendeley users who have this article in their library.

This artice is free to access.

Abstract

Background: In quantitative proteomics, peptide mapping is a valuable approach to combine positional quantitative information with topographical and domain information of proteins. Quantitative proteomic analysis of cell surface shedding is an exemplary application area of this approach.Results: We developed ImproViser (http://www.improviser.uni-freiburg.de) for fully automated peptide mapping of quantitative proteomics data in the protXML data. The tool generates sortable and graphically annotated output, which can be easily shared with further users. As an exemplary application, we show its usage in the proteomic analysis of regulated intramembrane proteolysis.Conclusion: ImproViser is the first tool to enable automated peptide mapping of the widely-used protXML format. © 2014 Videm et al.; licensee BioMed Central Ltd.

Cite

CITATION STYLE

APA

Videm, P., Gunasekaran, D., Schröder, B., Mayer, B., Biniossek, M. L., & Schilling, O. (2014). Automated peptide mapping and protein-topographical annotation of proteomics data. BMC Bioinformatics, 15(1). https://doi.org/10.1186/1471-2105-15-207

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free