The immune response in HPV+ oropharyngeal cancer

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Abstract

Although human papillomavirus (HPV)+ oropharyngeal cancers often present with metastasis, most patients have excellent long-term survival. The reason underlying such an apparent contradiction remains unclear, but we have recently demonstrated that the improved survival of HPV+ oropharyngeal cancer patients has an immunological component, as the levels of tumor-infiltrating lymphocytes (TILs) can be used to stratify HPV+ patients into high-risk and low-risk groups. © 2014 Landes Bioscience.

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King, E. V., Ottensmeier, C. H., & Thomas, G. J. (2014). The immune response in HPV+ oropharyngeal cancer. OncoImmunology, 3(1). https://doi.org/10.4161/onci.27254

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