Abstract
Background: Cooperation between transcription factors and myogenic regulatory factors is important for skeletal muscle differentiation. Results: sLZIP inhibits expression of muscle-specific genes during myogenesis via disruption of an association betweenα-actinin- 4 and MEF2. Conclusion: A novel myogenesis regulatory mechanism of sLZIP is characterized. Significance: sLZIP can be used as a therapeutic target for treatment of muscle diseases. © 2014 by The American Society for Biochemistry and Molecular Biology, Inc.
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An, H. T., Kim, J., Yoo, S., & Ko, J. (2014). Small leucine zipper protein (sLZIP) negatively regulates skeletal muscle differentiation via interaction with α-actinin-4. Journal of Biological Chemistry, 289(8), 4969–4979. https://doi.org/10.1074/jbc.M113.515395
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