Report from the “Global Health Meets Infection Biology” LSS2012 Program

Abstract

The proceedings contain 24 papers. The special focus in this conference is on Infection Biology. The topics include: Vaccines and global health; prevention of HIV-1 infection; viral parasites of human pathogens and their influence on disease; infectious diseases and changing lifestyles in developing countries; Wolbachia and the control of mosquito-borne diseases; comparative genomics of drug resistance in African trypanosomes; population genetics and genomics of genetically monomorphic bacterial pathogens; intracellular parasitism, the driving force of evolution of Legionella, the agent of legionnaire disease; PE_PGRS genetic diversity in mycobacterium tuberculosis is not related to immune escape; a peptidoglycan-anchored polysaccharide involved in cell wall biogenesis; toward a genetic theory of infectious diseases; great ape reservoirs of AIDS and malaria; vascular colonization by Neisseria meningitides; chronic salmonella carriage is controlled by a host regulator of fatty acid metabolism; single and united! essential virulence strategy of salmonella to evade the host defense; fine-tuned bistability stabilizes the cooperation-based intestinal virulence of salmonella; biochemical dissection of bacterial virulence and macrophage innate immunity; structure-based analysis of protein transport across bacterial membranes; infection and cancer; antibody-mediated treatment of infections using genetically modified bacteria and plants; force volume and stiffness tomography investigation of bacterial membranes; real-time single-cell imaging to analyze the growth dynamics and heterogeneity of mycobacterium tuberculosis during infection; dissecting the human T and B cell response to pathogens and enabling rational vaccine design with systems biology.