Although immune checkpoint inhibitors (ICIs) have dramatically revolutionized the field of oncology over the last decade, severe immune-related adverse events (irAEs) are potentially life-threatening. In comparison with toxicities involving the skin, gastrointestinal tract and endocrine system, nephrotoxicity is less common but often underestimated due to difficult diagnosis. Management usually consists of treatment discontinuation and/or corticosteroid use. In this review, we summarize current knowledge of ICI-induced nephrotoxicity, evaluating drawbacks and future perspectives.
CITATION STYLE
Catalano, M., Roviello, G., Galli, I. C., Santi, R., & Nesi, G. (2022, December 20). Immune checkpoint inhibitor induced nephrotoxicity: An ongoing challenge. Frontiers in Medicine. Frontiers Media S.A. https://doi.org/10.3389/fmed.2022.1014257
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