Abstract
The ionic liquid [H3N+CH2CH 2OH][CH3 COO-] (HEAA) catalyzes a three-component, one-pot condensation of malononitrile/ethyl cyanoacetate, 1,3-dicarbonyl compound/enol, and quinone or ninhydrin in water to afford a spiropyran derivative. This method has advantages of mild reaction conditions, short reaction time, and environmental friendliness.
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Jin, S. S., Ding, M. H., & Guo, H. Y. (2013). Ionic liquid catalyzed one-pot synthesis of spiropyran derivatives via three-component reaction in water. Heterocyclic Communications, 19(2), 139–143. https://doi.org/10.1515/hc-2012-0159
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