Here we describe a low-cost mobile device that combines cell-phone and satellite communication technologies with fluid miniaturization techniques for performing all essential functions of enzyme-linked immunosorbent assay (ELISA). Disease-specific antigens are immobilized on the microfluidic surface, and disease specific antibodies are captured on the surface and visualized with silver-gold amplification. The diagnostic result is automatically determined by the device by measuring the absorbance through the silver-gold amplification in the microchannel. The results are displayed for the user and are synchronized to a remote patient record. The overall system aims to be portable, robust, low-power, and fully utilize the ability of mobile devices for bringing better health care to resource poor areas.
CITATION STYLE
Guo, T. W., Laksanasopin, T., Sridhara, A. A., Nayak, S., & Sia, S. K. (2015). Mobile device for disease diagnosis and data tracking in resource-limited settings. Methods in Molecular Biology, 1256, 3–14. https://doi.org/10.1007/978-1-4939-2172-0_1
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