Cache Valley virus (CVV) is a mosquitoborne virus that infects livestock and humans. We report results of surveillance for CVV in New York, USA, during 2000-2016; full-genome analysis of selected CVV isolates from sheep, horse, humans, and mosquitoes from New York and Canada; and phenotypic characterization of selected strains. We calculated infection rates by using the maximum-likelihood estimation method by year, region, month, and mosquito species. The highest maximumlikelihood estimations were for Anopheles spp. mosquitoes. Our phylogenetic analysis identifi ed 2 lineages and found evidence of segment reassortment. Furthermore, our data suggest displacement of CVV lineage 1 by lineage 2 in New York and Canada. Finally, we showed increased vector competence of An. quadrimaculatus mosquitoes for lineage 2 strains of CVV compared with lineage 1 strains.
CITATION STYLE
Dieme, C., Ngo, K. A., Tyler, S., Maffei, J. G., Zink, S. D., Dupuis, A. P., … Kramer, L. D. (2022). Role of Anopheles Mosquitoes in Cache Valley Virus Lineage Displacement, New York, USA. Emerging Infectious Diseases, 28(2), 303–313. https://doi.org/10.3201/eid2802.203810
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