In vivo preclinical assays are required to screen potential agents that target the tumor vasculature. Here, a hollow fibre-based assay for the quantification of neovasculature in the presence or absence of an agent that potentially targets tumor neovasculature is described. The neovasculature is developed as a consequence of the presence of tumor cells encapsulated in hollow fibres, which are transplanted subcutaneously in the dorsal flanks of mice.
CITATION STYLE
Shnyder, S. D. (2009). Use of the hollow fibre assay for studies of tumor neovasculature. Methods in Molecular Biology (Clifton, N.J.), 467, 331–342. https://doi.org/10.1007/978-1-59745-241-0_21
Mendeley helps you to discover research relevant for your work.