Amplification of viral ribonucleic acid by real-time reverse transcriptase polymerase chain reaction is the gold standard to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, alternative reliable, fast, and cost-effective methods for the detection of SARS-CoV-2 are still needed. In this chapter, the mass spectrometry–based detection of amplified polymerase chain reaction products of SARS-CoV-2 genes from oral or nasopharyngeal swabs is described. The respective SARS-CoV-2 test has previously been shown to meet standard quality criteria and was therefore approved by the authorities in Europe and the USA.
CITATION STYLE
Wandernoth, P., Kriegsmann, K., Kriegsmann, J., & Kriegsmann, M. (2022). Detection of SARS-CoV-2 by Mass Spectrometry. In Methods in Molecular Biology (Vol. 2452, pp. 183–196). Humana Press Inc. https://doi.org/10.1007/978-1-0716-2111-0_12
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