Asymmetric cycloaddition and cascade addition–cyclization reactions

Abstract

The copper(I) catalysis has found a wide range of applications in the field of organic chemistry, due to its ability to promote various organic reactions and more notably in enantioselective transformations. Cu(I)-catalyzed asymmetric cycloaddition and cascade addition–cyclization reactions have proven to be one of the most efficient approaches for the stereoselective construction of diverse biologically important heterocycles. In this chapter, we will discuss the recent developments that have been reported in this area since 2010.