Using an in-house forensic toxicology database, we selected 1000 cases of driving under the influence of drugs (DUIDs) over a 12-month period if diazepam (D) and nordiazepam (ND) were both present in the blood samples. Quantitative analysis of D and ND in blood was done by solvent extraction (butyl acetate) and capillary column gas chromatography (GC) with a nitrogen-phosphorous (N-P) detector. The limits of quantitation of this analytical method for D and ND in blood were 0.05 mg/L. The correlation between D and ND concentrations in blood was statistically significant (r =.58, P
CITATION STYLE
Jones, A. W., & Holmgren, A. (2013). Concentrations of diazepam and nordiazepam in 1000 blood samples from apprehended drivers - Therapeutic use or abuse of anxiolytics? Journal of Pharmacy Practice, 26(3), 198–203. https://doi.org/10.1177/0897190012451910
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