N-alpha protein acetylation, catalyzed by N-alpha acetyltransferase complex, is a common protein -modification process in eukaryotic cells. Despite its widespread occurrence, the biological significance of this modification process is still unclear. We recently discovered a novel testis-predominant isoform of the catalytic subunit of the enzyme complex. Here, we describe the biochemical characterization of this testis-predominant N-alpha acetyltransferase complex, which includes protein-protein interaction study by co-immunoprecipitation experiment and functional study by N-alpha acetyltransferase assay. © 2012 Springer Science+Business Media, LLC.
CITATION STYLE
Pang, A. L. Y. (2012). Biochemical characterization of a testis-predominant isoform of N-alpha acetyltransferase. Methods in Molecular Biology, 825, 93–104. https://doi.org/10.1007/978-1-61779-436-0_8
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