Background: Long-COVID is emerging as a significant problem among individuals who recovered from COVID-19. Scant information is available on the prevalence, characteristics, and risk factors for long-COVID among people living with HIV (PLHIV). Setting: A tertiary level, private, HIV clinic in western India. Methods: A prospective, observational study was conducted to assess the prevalence of long-COVID among PLHIV. Long-COVID was defined as the presence of at least one symptom after 30 days of illness onset. A questionnaire for assessing general, cardiorespiratory, neuro-psychiatric, and gastro-intestinal symptoms was used to screen individuals with history of confirmed COVID-19. Data on demographics, HIV-related variables, comorbidities, and severity of COVID-19 were abstracted from electronic medical records. Univariate and multivariate logistic regression were used to identify risk factors for long-COVID. Results: Ninety-four PLHIV were screened for long-COVID. Median (interquartile range [IQR]) age was 51 (47–56) years and 73.4% were males. The majority (76.6%) had a history of asymptomatic–mild COVID-19 illness. The prevalence of long-COVID was 43.6% (95% confidence interval [CI], 33.4–54.2). Moderate–severe COVID-19 illness was significantly associated with long-COVID (adjusted odds ratio, 4.7; 95% CI, 1.4–17.9; p =.016). Among individuals with long-COVID, cough (22.3%) and fatigue (19.1%) were the commonest symptoms. The median (IQR) duration for resolution of symptoms was 15 (7–30) days. Ten individuals (10.6%) had persistent symptoms at a median of 109 days since the onset of COVID-19. Conclusion: Long-COVID is common among PLHIV with moderate–severe acute COVID-19 illness. There is a need for integration of long-COVID diagnosis and care services within antiretroviral therapy clinics for PLHIV with COVID-19.
CITATION STYLE
Pujari, S., Gaikwad, S., Chitalikar, A., Dabhade, D., Joshi, K., & Bele, V. (2021). Long-coronavirus disease among people living with HIV in western India: An observational study. Immunity, Inflammation and Disease, 9(3), 1037–1043. https://doi.org/10.1002/iid3.467
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