MP70-06 POST-TREATMENT MRI FOR ASSESSMENT OF FOCAL THERAPY TREATMENT RESPONSE

Abstract

INTRODUCTION AND OBJECTIVE: Focal therapy may preserve quality of life while offering cancer control for appropriately selected men. The need for biopsy post-ablation is controversial and there is limited data regarding the performance of MRI in the posttreatment setting. We aim to assess the performance of multiparametric prostate MRI for treatment success/failure in men undergoing focal ablation for prostate cancer. METHOD(S): A retrospective review of men with clinically localized prostate cancer undergoing focal ablation (nanoparticle-direct focal laser ablation, high intensity focused ultrasound, or cryoablation from 9/ 2017 to 10/2019. All patients underwent preoperative prostate MRI with repeat imaging post ablation at 3-6 months with subsequent targeted mapping biopsy of the ablation zone. Delphi consensus criteria for success after focal therapy was defined at absence of at gleason pattern 4 and grade group 1 cancer core length