Ultrasound-Fluoroscopy fusion is a key step toward intra-operative dosimetry for prostate brachytherapy. We propose a method for intensity-based registration of fluoroscopy to ultrasound that obviates the need for seed segmentation required for seed-based registration. We employ image thresholding and morphological and Gaussian filtering to enhance the image intensity distribution of ultrasound volume. Finally, we find the registration parameters by maximizing a point-to-volume similarity metric. We conducted an experiment on a ground truth phantom and achieved registration error of 0.7±0.2mm. Our clinical results on 5 patient data sets show excellent visual agreement between the registered seeds and the ultrasound volume with a seed-to-seed registration error of 1.8±0.9mm. With low registration error, high computational speed and no need for manual seed segmentation, our method is promising for clinical application. © 2011 Springer-Verlag.
CITATION STYLE
Dehghan, E., Lee, J., Fallavollita, P., Kuo, N., Deguet, A., Burdette, E. C., … Fichtinger, G. (2011). Point-to-volume registration of prostate implants to ultrasound. In Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) (Vol. 6892 LNCS, pp. 615–622). https://doi.org/10.1007/978-3-642-23629-7_75
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