Red blood cell transfusion triggers and transfusion alternatives in elective orthopedic hip and knee replacement surgery – a review

Abstract

In elective hip and knee replacement surgery, the use of red blood cell transfusion alternatives has been widely accepted. However, nowadays, more evidence is accumulating that suggests some transfusion alternatives may no longer be cost effective. In this review, an evidence-based overview of the applied transfusion alternatives is provided, aiming for optimal and cost-effective patient blood management in elective hip and knee replacement surgery.