Some new methods and practical strategies for the efficient resolution of a wide variety of organic componds by means of such crystallization procedures as preferential crystallization, diastereomeric salt formation and their combination are described. Utilizing the organic compounds with high optical purities thus obtained, application study in the following field has been performed; 1) verification of the Brewster's theory of optical activity, 2) syntheses of pharmaceutical, agricultural and perfuming chemicals, 3) preparation of optical purity determining agents, 4) preparation of atropisomeric bis (triarylphosphine) as a catalyst for asymmetric hydrogenation, 5) syntheses of ferroelectric liquid crystals. In this article, an outline of our investigation in the above mentioned fields is also described. © 1992, The Society of Synthetic Organic Chemistry, Japan. All rights reserved.
CITATION STYLE
Nohira, H. (1992). Optical Resolution of Organic Compounds by Means of Crystallization and Their Applications. Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry, 50(1), 14–23. https://doi.org/10.5059/yukigoseikyokaishi.50.14
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