Recombinant DNA production of spider silk proteins

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Abstract

Spider dragline silk is considered to be the toughest biopolymer on Earth due to an extraordinary combination of strength and elasticity. Moreover, silks are biocompatible and biodegradable protein-based materials. Recent advances in genetic engineering make it possible to produce recombinant silks in heterologous hosts, opening up opportunities for large-scale production of recombinant silks for various biomedical and material science applications. We review the current strategies to produce recombinant spider silks. © 2013 The Authors. Microbial Biotechnology published by John Wiley & Sons Ltd and Society for Applied Microbiology.

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Tokareva, O., Michalczechen-Lacerda, V. A., Rech, E. L., & Kaplan, D. L. (2013, November). Recombinant DNA production of spider silk proteins. Microbial Biotechnology. https://doi.org/10.1111/1751-7915.12081

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