Low-dose selective arterial calcium stimulation test for localizing insulinoma: A single-center experience of five consecutive cases

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Abstract

The selective arterial calcium stimulation test (SACST) is one of the most useful localization tests for insulinoma but can cause false-positive and/or unexpected multi arterial positive results that hamper clinical decisions. There are also several adverse effects, such as nausea and hypoglycemia, at the conventional dose (0.025 mEq/kg) of calcium injection. We herein report five consecutive insulinoma cases in which low-dose (0.005-0.007 mEq/kg) calcium injection for SACST led to successful insulinoma localization. No adverse effects of SACST were observed. In conclusion, a low-dose SACST can be a favorable option as an insulinoma localization test in terms of accuracy and safety.

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Hatoko, T., Murakami, T., Sone, M., Yabe, D., Masui, T., Nakamoto, Y., … Inagaki, N. (2020). Low-dose selective arterial calcium stimulation test for localizing insulinoma: A single-center experience of five consecutive cases. Internal Medicine, 59(19), 2397–2403. https://doi.org/10.2169/internalmedicine.4396-20

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