Effect of graded hypothermia (27° to 34°c) on behavioral function, histopathology, and spinal blood flow after spinal ischemia in rat

Abstract

Background and Purpose We used a rat model of reversible spinal ischemia to assess the effect of spinal cord temperature on the development of neurological and histopathologic changes after 20 minutes of reversible aortic occlusion. Spinal cord blood flow and CO2 reactivity was tested by using laser Doppler before and 60 minutes after ischemia. Methods In halothane. © 1994 American Heart Association, Inc.