Effects of streptozotocin-induced diabetes on receptive and proceptive behaviors in female rats.

Abstract

Sexual dysfunction in diabetic men is thoroughly recognized, while not yet done in diabetic women. Recently, Streptozotocin (STZ)-induced male rats showed a significantly depressed copulatory behavior, compared with normal animals. We investigated whether STZ-induced diabetic female rats would produce observable deficits in sexual behavior. Results in the present study are the first to show that STZ-induced diabetic female rats have a depressed sexual behavior.