Biosensors for the control of some toxins, viral and microbial infections to prevent actions of bioterrorists

Abstract

Foodborne toxins are very widespread and very dangerous for health of people. It is very important to control the level of T2 mycotoxin which has a high toxic effect and may serve as biological weapons and agent for bioterrorism. From other side Salmonellosis is the most common enteric infection. Retroviral bovine leucosis is very dangerous too since the level of ailing people correlates with the amount of sick animals in the area of habitat. The most effective way to prevent not desirable results is in constant monitoring of the epidemiological situation. It may be done with the help of instrumental -analytical approaches based on the principles of biosensorics. They may provide selective, high sensitive, simple and express analysis which may be fulfilled in "on line" regime and in field conditions. These approaches may be completed by the special GSM system for immediately transferring results of analysis in the specialized laboratory for appropriate action. In the article the development of authors of the immune biosensors for monitoring of toxins, bacteria and biochemical diagnostics of retroviral leukemia through analysis of blood and milk are analyzed. The main attention is paid the optical biosensors based on the surface plasmon resonance (SPR) and total internal reflection ellipsometry (TIRE) as well as photoluminescence (PhL) and photoconductivity (PhC) of nanostructured (sNPS) porous silicon. The characteristics of the immune biosensors may be changed by varying procedures of the preliminary preparation of the transducer surface. The special attention is paid to the developed procedures of the preparation of samples for analysis. At the final part of article in short form the preliminary results obtained at the application of some approaches for the simple and rapid decontamination of aquatic environments from number of toxic substances are considered. © 2012 Springer Science+Business Media B.V.