Clinical aspects of testicular carcinoma‐in‐situ

Abstract

Carcinoma‐in‐situ germ cells were demonstrated in testicular biopsies from 9 of 826 patients (1.1%) from a selected group of Danish infertile men. A similar observation was noted in testicular biopsies from 9 Swiss patients (representing 0.55% of the total number of infertile patients biopsied in that study). Such changes were also seen in 8 testicular biopsies from the contralateral testis of 180 patients (4.4%) with carcinoma of the teitis. Moreover, carcinoma‐in‐situ has beer, found in maldecended testes and in gonads of patients with the testicular feminization syndrome although the incidence of carcinoma‐in‐situ in these two latter groups is unknown. The malignant potential of carcinoma‐in‐situ of the testis in infertile men has been clearly demonstrated, whereas its clinical significance in other groups of patients remains to be determined. Copyright © 1981, Wiley Blackwell. All rights reserved