Chikungunya virus-induced autophagy and apoptosis

Abstract

This chapter focuses on two major host responses recently found to be involved in CHIKV infection: autophagy and apoptosis. For each process, we first present molecular pathways and associated signalling, then we highlight the diverse strategies developed by host cells to prevent viral replication and virus-induced cell death, as well as by the virus to fight and hijack these host cell defence pathways.