Soil-derived microorganisms have been sampled intensively throughout the last decades in order to discover bacterial strains that produce new antibiotics. The increasing emergence of multidrug-resistant bacteria and the constant high demand for new antibiotic classes are leading to the sampling and investigation of new microbiomes that contain antimicrobial producers. Human-associated microbiomes are therefore gaining more and more attention. This chapter presents a detailed description of how human microbiomes can be sampled and how microbiota members from skin and nasal samples can be isolated. Different methods for antimicrobial compound screening are presented.
CITATION STYLE
Torres Salazar, B., Lange, A., Camus, L., & Heilbronner, S. (2023). Sampling of Human Microbiomes to Screen for Antibiotic-Producing Commensals. In Methods in Molecular Biology (Vol. 2601, pp. 39–54). Humana Press Inc. https://doi.org/10.1007/978-1-0716-2855-3_3
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