Flavonoids from the Fresh Leaves of Kalanchoe tomentosa (Crassulaceae)

Abstract

Flavonoids compounds such as kaempferol ( 1 ), kaempferol-3- O -β-D-glucopyranoside or astragalin ( 2 ) and kaempferol-3- O -α-L-rhamnoside or afzelin ( 3 ) have been isolated from the fresh leaves of Kalanchoe tomentosa (Crassulaceae). The chemical structure of isolated compounds 1-3 were identified by spectroscopic evidences and comparison with those compound previously reported. Compounds 1-3 showed cytotoxic activity against P-388 murine leukimia cells with IC 50 values of 51.8, > 100 and 3.32 µg/mL, respectively.