The role of Microglia in neuroinflammation

Abstract

Microglia play a critical role in innate immunity in the central nervous system (CNS). The activation of these calls is also observed in various psycho-neurological disorders. In this context, microglia may control the pathological processes to maintain the homeostasis of the CNS. However, microglia are also key players in neuroinflammation and induce chronic neuronal damage. Thus, microglial activation represents a potential therapeutic target in various neurological disorders.