Utility of a commercial PCR assay and a clinical prediction rule for detection of toxigenic clostridium difficile in asymptomatic carriers

Curtis J. Donskey; Venkata C.K. Sunkesula; Annette L. Jencson; Nimalie D. Stone; Carolyn V. Gould; L. Clifford McDonald; Matthew Samore; Jeanmarie Mayer; Susan Pacheco; Susan Sambol; Laurica Petrella; Deborah Terry; Dale N. Gerding

Journal ArticleOPEN ACCESS

Utility of a commercial PCR assay and a clinical prediction rule for detection of toxigenic clostridium difficile in asymptomatic carriers

Journal of Clinical Microbiology (2014) 52(1) 315-318

DOI: 10.1128/JCM.01852-13

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Abstract

A commercial PCR assay of perirectal swab specimens detected 17 (68%) of 25 asymptomatic carriers of toxigenic Clostridium difficile, including 93% with skin and/or environmental contamination. A clinical prediction rule, followed by PCR screening, could be used to identify carriers at high risk of C. difficile shedding.Copyright © 2014, American Society for Microbiology. All Rights Reserved.

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Donskey, C. J., Sunkesula, V. C. K., Jencson, A. L., Stone, N. D., Gould, C. V., McDonald, L. C., … Gerding, D. N. (2014). Utility of a commercial PCR assay and a clinical prediction rule for detection of toxigenic clostridium difficile in asymptomatic carriers. Journal of Clinical Microbiology, 52(1), 315–318. https://doi.org/10.1128/JCM.01852-13

Utility of a commercial PCR assay and a clinical prediction rule for detection of toxigenic clostridium difficile in asymptomatic carriers

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