Congenital mitral regurgitation

Abstract

This is commonly due to an isolated cleft in the anterior mitral valve (MV) leaflet or the effect of MV leaflets dysplasia with evidence of shortened and fused chordae. In patients with an isolated MV cleft, the defect in the anterior MV leaflet points toward the left ventricular (LV) outflow tract, not like in cases with atrioventricular septal defect (AVSD). As a rule, larger clefts in the anterior MV leaflet will create greater degrees of mitral regurgitation (MR).