Pesticide Toxicity Associated with Infertility

Abstract

Pesticides have benefited mankind in many ways like agriculture, industrial and health sectors. On the other hand, conversely their deleterious effects in both, humans and animals are also alarming. Pesticides including organophosphates, organochlorines, carbamates, pyrethrins and pyrethroids are found sufficiently in the environment resulting in everyday human exposure. This is of a huge concern because most of the pesticides are known to target all the physiological functions of both humans and animals. Indeed, reproduction, being one of the most important physiological processes, that is affected by the daily exposure to pesticides and leading to infertility issues. The present study summarizes the exposure of men and women to certain pesticides resulting in different infertility concerns like sperm abnormalities, decreased fertility, abnormal sperm count and motility, testicular atrophy, ovarian dysfunction, spontaneous abortions, disruption of hypothalamic–pituitary–gonadal axis, etc. So, this article will be helpful in perceiving the mechanism of reproductive toxicity of different pesticides and their management before any alarm of danger.