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Controlling Fucosylation Levels of Antibodies with Osmolality during Cell Culture

  • Konno Y
  • Kobayashi Y
  • Takahashi K
  • et al.
Springer Netherlands, (2010), 121-125
DOI: 10.1007/978-90-481-3892-0_20
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Abstract

Because defucosylation levels (deFuc%) of monoclonal antibodies (MAbs) must be regulated for quality control, it is quite important to analyze the factors that affect deFuc%. For the MAbs produced in the rat hybridoma cell line YB2/0, we found that osmolality of the...

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Konno, Y., Kobayashi, Y., Takahashi, K., Takahashi, E., Sakae, S., Wakitani, M., … Hosoi, S. (2010). Controlling Fucosylation Levels of Antibodies with Osmolality during Cell Culture. In Basic and Applied Aspects (pp. 121–125). Springer Netherlands. https://doi.org/10.1007/978-90-481-3892-0_20

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