Correlation analysis of the vertebral compression degree and CT HU value in elderly patients with osteoporotic thoracolumbar fractures

Abstract

Background: To explore the correlation of the vertebral compression degree and cancellous bone CT HU in elderly patients with osteoporotic thoracolumbar fractures. Methods: Elderly patients with single-segment vertebral fragility fractures were retrospectively reviewed. All patients experienced a low-energy trauma and underwent thoracolumbar MRI. The consistency of measurement between two spine surgeons was evaluated. The average CT HU value of the adjacent vertebral body was used instead. Results: A total of 54 patients were included in the final analysis. The patients’ average age was 70.39 ± 8.53 years, and the average CT HU value was 72.78 ± 29.75 HU. The average vertebral compression ratio was 0.57 ± 0.16. Measurements showed both good intrarater repeatability and good interrater reproducibility of the vertebral compression ratio (ICC = 0.978). The degree of vertebral compression in thoracolumbar osteoporotic fractures was strongly positively correlated with the cancellous bone CT HU value (P < 0.01). Conclusions: The local bone quality as evaluated by the CT HU value is an important factor affecting the degree of compression in osteoporotic vertebral fractures. This study provides quantitative evidence that a greater compression ratio with thoracolumbar osteoporotic fractures was associated with lower bone density in elderly patients. Further longitudinal studies with larger cohorts are needed to verify this relationship.