Serovariedades de Leptospira y riesgos de contagio en humanos y perros de la ciudad de Culiacán, Sinaloa, México

Abstract

This work aimed to identify the Leptospira interrogans serovar and the risk factors in humans and dogs in shared areas, 247 samples of human serum, were analyzed by the Micro Agglutination technique (MAT), prior informed consent from public hospital blood banks. To obtain information from the participants regarding the presence of dogs a survey was used. A total of 106 dog sera samples were collected inside and outside the homes of seropositive humans and analyzed by MAT. The statistical analysis consisted of a Pearson's Chi square test of homogeneity. The OR estimation was made using a simple logistic regression model using the Stata Intercooled version 13.1 program. Five serovars were detected in humans; from the highest to the lowest frequency, these were: Canicola, Icterohaemorrhagiae, Pyrogenes, Autumnalis, and Pomona. Eleven serovars were identified in dogs: Wolffi, Bratislava, Australis, Canicola, Grippotyphosa, Pyrogenes, Hardjo, Icterohaemorrhagiae, Pomona, Hebdomadis, and Shermani. All the serovar present in dogs were also observed in humans, the serovariety Autumnalis is not included in the dog search panel. The main risk factor for humans was job occupation (p <0.05); in dogs, it was sex, with females being at greater risk (p<0.05, OR = 2.9) of infection. A total of 12 serovars were identified among humans and dogs.