The assembly line is one of the key features of industrial production on the macroscopic scale, allowing programmability and sequential addition of parts to a final product. In this chapter, we use DNA to extend this notion to the nanoscale by the judicious combination of three DNA-based components: a DNA origami tile that provides a framework and track for the assembly process, three two-state DNA cassettes that can be programmed to donate cargo and are attached to the tile, and a DNA walker that can move on the track to collect cargo.
CITATION STYLE
Zhang, X., Ding, X., Zou, J., & Gu, H. (2017). A proximity-based programmable DNA nanoscale assembly line. In Methods in Molecular Biology (Vol. 1500, pp. 257–268). Humana Press Inc. https://doi.org/10.1007/978-1-4939-6454-3_18
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