Underlying principles in ejaculatory and orgasmic function and dysfunction in the male

Abstract

Since sexual function relies on a myriad of complex interactions between neuroanatomical, biochemical, and psychosocial factors, understanding the mechanisms driving various sexual dysfunctions has been challenging. Our understanding of numerous mechanisms involved in male sexual function has been enhanced over the past several decades utilizing a variety of techniques ranging from animal models to human studies. Although studies of these conditions remain limited, the application of new investigative techniques, including molecular imaging and genetic analyses, will deepen our understanding of ejaculatory and orgasmic function. In this chapter, we discuss the neuroanatomical and biochemical pathways related to ejaculatory and orgasmic function and the promising future of investigation evaluating these conditions.