The prefrontal cortex underlies our high order cognitive abilities and is the target of projections from many neuromodulatory nuclei. The dorsolateral prefrontal cortex is particularly critical for rule representation and working memory, or the ability to hold information “in mind” in the absence of sensory input. Emerging evidence supports a prominent and permissive role for acetylcholine in these excitatory circuits, through actions at cholinergic nicotinic receptors. Here we review the involvement of acetylcholine in working memory via actions at nicotinic receptors.
CITATION STYLE
Galvin, V. C., Arnsten, A. F. T., & Wang, M. (2020). Involvement of nicotinic receptors in working memory function. In Current Topics in Behavioral Neurosciences (Vol. 45, pp. 89–99). Springer Science and Business Media Deutschland GmbH. https://doi.org/10.1007/7854_2020_142
Mendeley helps you to discover research relevant for your work.