This paper raises the need for a systematic evaluation of non-linear interaction between various turbulent-driven physical processes in fermentors. Various turbulent/mixing studies published in the literature are formalized based on a multidimensional framework. This formalization leads us to the limitations of many existing approaches and scale-up rules to mixing problems. The results on the effects of micromixing and fluid shear on yeast cells will be presented as an example to show the possibility of a non-linear interaction. A micro-environmental approach is proposed whereby the effects of multiple turbulent-driven physical processes in the micro-environments of cells can be evaluated.
CITATION STYLE
Namdev, P. K., Dunlop, E. H., Wenger, K., & Villenueve, P. (1994). Role of Turbulence in Fermentations. In Advances in Bioprocess Engineering (pp. 149–156). Springer Netherlands. https://doi.org/10.1007/978-94-017-0641-4_21
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