Asynchronous detected disappearance of the pro-nuclei by time-lapse X embryonic development

Abstract

Objective: To investigate whether pro-nuclei disappearance synchronicity would have something to do with blastomere cleavage time up to D3 (timeline) and if it would be associated with the appearance of embryo abnormalities. Methods: The sample of the present study was designed with 100 embryos (n = 100). With the aid of an embryonic analysis equipment: Time-Lapse, we studied embryonic morphokinetics from the zygote stage to D3. Results: When there was no pronuclei synchronous disappearance, 30.8% underwent normal cleavage, whereas when there was pronuclei synchronous disappearance, 44.8% had normal cleavage. When there was no pronuclei synchronous disappearance, 46.2% had some type of abnormality, whereas when there was pronuclei synchronous disappearance, 56.3% had some kind of abnormality. Conclusion: Although the statistical results were not significant, we believe that with a larger sample size we could state with higher reliability, that the pro-nuclei synchronous disappearance analysis may, in the near future, indicate higher embryo quality.