Letters of the English alphabet have heretofore been used to name tetracycline resistance determinants. Since all 26 letters have now been used, a nomenclature employing numerals is recommended for future determinants, and one laboratory has offered to coordinate the assignment of numerals.
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Levy, S. B., McMurry, L. M., Barbosa, T. M., Burdett, V., Courvalin, P., Hillen, W., … Taylor, D. E. (1999). Nomenclature for new tetracycline resistance determinants. Antimicrobial Agents and Chemotherapy, 43(6), 1523–1524. https://doi.org/10.1128/aac.43.6.1523