Perfusion CT: Technical aspects

Abstract

Perfusion CT is a high temporal resolution dynamic contrast-enhanced CT imaging technique that enables us to evaluate the functional blood supply to an organ or tissue of interest. This technique was first described in the 1970s, but it has reached its clinical potential in recent years due to a recognised clinical need in stroke and oncology and technological advances in acquisition and post-processing methods that have facilitated its clinical implementation. Qualitative and quantitative parameters derived from perfusion CT facilitate therapeutic triage and enable downstream treatment effects on the vasculature to be assessed. This chapter discusses the principles of perfusion CT and its clinical implementation.