MOSAiCS-HMM: A Model-Based Approach for Detecting Regions of Histone Modifications from ChIP-Seq Data

  • Chung D
  • Zhang Q
  • Keleş S
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Abstract

Abstract Chromatin immunoprecipitation followed by high throughput sequencing ( ChIP - seq ) experiments are routinely utilized for studying epigenomics of transcriptional regulation. We review some of the important statistical issues in the analysis of these experiments ...

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Chung, D., Zhang, Q., & Keleş, S. (2014). MOSAiCS-HMM: A Model-Based Approach for Detecting Regions of Histone Modifications from ChIP-Seq Data. In Statistical Analysis of Next Generation Sequencing Data (pp. 277–295). Springer International Publishing. https://doi.org/10.1007/978-3-319-07212-8_14

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