Multiple mechanisms contribute to the physiological regulation of G protein-coupled receptors (GPCRs) present in the plasma membrane, the main site where ligand-induced signaling events are initiated. Early studies delineated the existence of distinct functional processes of receptor regulation in natively expressing cells and tissues (1,2). More recent studies have led to an explosion of new information regarding cellular and molecular mechanisms of receptor regulation.
CITATION STYLE
Hislop, J. N., & von Zastrow, M. (2005). Regulated Membrane Trafficking and Proteolysis of GPCRs. In Contemporary Clinical Neuroscience (pp. 95–105). Springer Nature. https://doi.org/10.1007/978-1-59259-919-6_4
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