Electron tomographic reconstructions often contain artefacts from sources such as noise in the projections and a “missing wedge” of projection angles which can hamper quantitative analysis. We present a machine-learning approach using freely available software for analysing imperfect reconstructions to be used in place of the more traditional thresholding based on grey-level technique and show that a properly trained image classifier can achieve manual levels of accuracy even on heavily artefacted data, though if multiple reconstructions are being processed, a separate classifier will need to be trained on each reconstruction for maximum accuracy.
CITATION STYLE
Staniewicz, L., & Midgley, P. A. (2015). Machine learning as a tool for classifying electron tomographic reconstructions. Advanced Structural and Chemical Imaging, 1(1). https://doi.org/10.1186/s40679-015-0010-x
Mendeley helps you to discover research relevant for your work.