Swallowing in sleep and wakefulness in adult cats

Abstract

Clinical evidence indicates that swallowing, a vital function, may be impaired in sleep. To address this issue, we elicited swallows in awake and sleeping adult cats by injecting water through a nasopharyngeal tube. Our results indicate that swallowing occurs not only in non-rapid eye movement (NREM) sleep, but also in rapid eye movement (REM) sleep. In NREM sleep, the injections often caused arousal followed by swallowing, but, in the majority of cases, swallowing occurred in NREM sleep before arousal. These swallows in NREM sleep were entirely comparable to swallows in wakefulness. In contrast, the injections in REM sleep were less likely to cause arousal, and the swallows occurred as hypotonic events. Furthermore, apneas were sometimes elicited by the injections in REM sleep, and there was repetitive swallowing upon arousal. These results suggest that the hypotonic swallows of REM sleep were ineffective.