A Rare Case of Insular Epilepsy: Not To Be Missed in Refractory Epilepsy Patients

Abstract

Insular epilepsy often goes under-recognized and misdiagnosed due to the similarity of its features with temporal lobe epilepsy and the common exclusion of the insula during intracranial electroencephalography (iEEG). Here, we present a case of medically refractory epilepsy in a 43-year-old male with a 12-year history of tonic-clonic seizures. Insular epilepsy cases are often considered for diagnosis in the setting of abnormal insular pathology, such as a low-grade central nervous system (CNS) lesion. This is a unique case of non-lesional insular epilepsy, successfully managed by the resection of the insular cortex.